Derived from the husks of the plantago ovata, Psyllium is best known for its use a laxative. Psyllium has quite a few other benefits as well, particularly for the pancreas and heart.
Psyllium is a bulk-forming laxative, meaning that it absorbs intestinal liquid. This results in a softer, viscus-fluid-like stool. The greatest benefit of bulk-forming laxatives it that they are gradual and lacking side effects inherent to stimulant laxatives. If using psyllium as a bulk laxative, ensure taking the proper dosage, drinking with at least 8oz of water and follow with a second glass of water. Be mindful that psyllium may be an allergen and consider speaking to a medical professional before using.
Psyllium is used for reducing cholesterol levels, improving heart health. As other high-fibre foods, it can reduce the risk of heart disease by lowering blood pressure, strengthening the heart muscle, and improving lipid levels.
Evidence suggests that psyllium husks help to balance the glycemic balance. This involves the relationship between insulin and blood sugar; therefore, psyllium husks may benefit individuals with diabetes.
Psyllium husks are indicated as a pro-biotic and for weight loss as well.
Please use moderation and care when using herbs and read our disclaimer
6784680
{6784680:K6TQP3WA},{6784680:8WZGLMBM},{6784680:CX5RCXDP},{6784680:Z88TQ6YF},{6784680:6CIIEKCK}
1
apa
50
default
1438
https://lae.nfa.temporary.site/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%226CIIEKCK%22%2C%22library%22%3A%7B%22id%22%3A6784680%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Abutair%20et%20al.%22%2C%22parsedDate%22%3A%222016%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BAbutair%2C%20A.%20S.%2C%20Naser%2C%20I.%20A.%2C%20%26amp%3B%20Hamed%2C%20A.%20T.%20%282016%29.%20Soluble%20fibers%20from%20psyllium%20improve%20glycemic%20response%20and%20body%20weight%20among%20diabetes%20type%202%20patients%20%28randomized%20control%20trial%29.%20%26lt%3Bi%26gt%3BNutrition%20Journal%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B15%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%2086.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12937-016-0207-4%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12937-016-0207-4%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Soluble%20fibers%20from%20psyllium%20improve%20glycemic%20response%20and%20body%20weight%20among%20diabetes%20type%202%20patients%20%28randomized%20control%20trial%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ayman%20S.%22%2C%22lastName%22%3A%22Abutair%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ihab%20A.%22%2C%22lastName%22%3A%22Naser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Amin%20T.%22%2C%22lastName%22%3A%22Hamed%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Water-soluble%20dietary%20fibers%20intake%20may%20help%20control%20blood%20glucose%20and%20body%20weight.%5CnOBJECTIVE%3A%20The%20objective%20of%20the%20study%20was%20to%20determine%20whether%20soluble%20fiber%20supplementation%20from%20psyllium%20improves%20glycemic%20control%20indicators%20and%20body%20weight%20in%20type%202%20diabetic%20patients.%5CnMETHOD%3A%20Forty%20type%202%20diabetes%20patients%2C%20non-smoker%2C%20aged%20%26gt%3B35%5Cu00a0years%20were%20stratified%20to%20different%20strata%20according%20to%20sex%2C%20age%2C%20body%20mass%20index%20%28BMI%29%20and%20fasting%20blood%20sugar%20level%20%28FBS%29%20and%20randomly%20assigned%20into%20two%20groups%3B%20The%20intervention%20group%20which%20consists%20of%2020%20participants%20was%20on%20soluble%20fiber%20%2810.5%5Cu00a0g%20daily%29%2C%20and%20the%20control%20group%20which%20consist%20of%2020%20participants%20continued%20on%20their%20regular%20diet%20for%20eight%20weeks%20duration.%5CnRESULTS%3A%20After%208%5Cu00a0weeks%20of%20intervention%2C%20soluble%20fiber%20supplementation%20showed%20significant%20reduction%20in%20the%20intervention%20group%20in%20BMI%20%28p%5Cu2009%26lt%3B%5Cu20090.001%29%20when%20compared%20with%20the%20control%20group.%20Moreover%2C%20water%20soluble%20fiber%20supplementation%20proven%20to%20improve%20FBS%20%28163%20to%20119%5Cu00a0mg%5C%2Fdl%29%2C%20HbA1c%20%288.5%20to%207.5%5Cu00a0%25%29%2C%20insulin%20level%20%2827.9%20to%2019.7%20%5Cu03bcIU%5C%2FmL%29%2C%20C-peptide%20%285.8%20to%203.8%5Cu00a0ng%5C%2Fml%29%2C%20HOMA.IR%20%2811.3%20to%205.8%29%20and%20HOMA-%5Cu03b2%20%25%20%28103%20to%20141%5Cu00a0%25%29.%5CnCONCLUSION%3A%20The%20reduction%20in%20glycemic%20response%20was%20enhanced%20by%20combining%20soluble%20fiber%20to%20the%20normal%20diet.%20Consumption%20of%20foods%20containing%20moderate%20amounts%20of%20these%20fibers%20may%20improve%20glucose%20metabolism%20and%20lipid%20profile%20in%20type%202%20diabetes%20patients.%5CnTRIAL%20REGISTRATION%3A%20Current%20Controlled%20Trials%20PHRC%5C%2FHC%5C%2F28%5C%2F15%20.%22%2C%22date%22%3A%2210%2012%2C%202016%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12937-016-0207-4%22%2C%22ISSN%22%3A%221475-2891%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22U8LU2X8Y%22%5D%2C%22dateModified%22%3A%222020-08-31T08%3A12%3A36Z%22%7D%7D%2C%7B%22key%22%3A%22Z88TQ6YF%22%2C%22library%22%3A%7B%22id%22%3A6784680%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Garg%22%2C%22parsedDate%22%3A%222017%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BGarg%2C%20P.%20%282017%29.%20Psyllium%20Husk%20Should%20Be%20Taken%20at%20Higher%20Dose%20with%20Sufficient%20Water%20to%20Maximize%20Its%20Efficacy.%20%26lt%3Bi%26gt%3BJournal%20of%20the%20Academy%20of%20Nutrition%20and%20Dietetics%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B117%26lt%3B%5C%2Fi%26gt%3B%285%29%2C%20681.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jand.2017.03.001%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jand.2017.03.001%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Psyllium%20Husk%20Should%20Be%20Taken%20at%20Higher%20Dose%20with%20Sufficient%20Water%20to%20Maximize%20Its%20Efficacy%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pankaj%22%2C%22lastName%22%3A%22Garg%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%2205%202017%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.jand.2017.03.001%22%2C%22ISSN%22%3A%222212-2672%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22U8LU2X8Y%22%5D%2C%22dateModified%22%3A%222020-08-31T08%3A12%3A33Z%22%7D%7D%2C%7B%22key%22%3A%228WZGLMBM%22%2C%22library%22%3A%7B%22id%22%3A6784680%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Erdogan%20et%20al.%22%2C%22parsedDate%22%3A%222016%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BErdogan%2C%20A.%2C%20Rao%2C%20S.%20S.%20C.%2C%20Thiruvaiyaru%2C%20D.%2C%20Lee%2C%20Y.%20Y.%2C%20Coss%20Adame%2C%20E.%2C%20Valestin%2C%20J.%2C%20%26amp%3B%20O%26%23x2019%3BBanion%2C%20M.%20%282016%29.%20Randomised%20clinical%20trial%3A%20mixed%20soluble%5C%2Finsoluble%20fibre%20vs.%20psyllium%20for%20chronic%20constipation.%20%26lt%3Bi%26gt%3BAlimentary%20Pharmacology%20%26amp%3B%20Therapeutics%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B44%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%2035%26%23x2013%3B44.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fapt.13647%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fapt.13647%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Randomised%20clinical%20trial%3A%20mixed%20soluble%5C%2Finsoluble%20fibre%20vs.%20psyllium%20for%20chronic%20constipation%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Erdogan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%20S.%20C.%22%2C%22lastName%22%3A%22Rao%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Thiruvaiyaru%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Y.%20Y.%22%2C%22lastName%22%3A%22Lee%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22E.%22%2C%22lastName%22%3A%22Coss%20Adame%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Valestin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22O%27Banion%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Fibre%20supplements%20are%20useful%2C%20but%20whether%20a%20plum-derived%20mixed%20fibre%20that%20contains%20both%20soluble%20and%20insoluble%20fibre%20improves%20constipation%20is%20unknown.%5CnAIM%3A%20To%20investigate%20the%20efficacy%20and%20tolerability%20of%20mixed%20soluble%5C%2Finsoluble%20fibre%20vs.%20psyllium%20in%20a%20randomized%20double-blind%20controlled%20trial.%5CnMETHODS%3A%20Constipated%20patients%20%28Rome%20III%29%20received%20mixed%20fibre%20or%20psyllium%2C%205%20g%20b.d.%2C%20for%204%20weeks.%20Daily%20symptoms%20and%20stool%20habit%20were%20assessed%20using%20stool%20diary.%20Subjects%20with%20%5Cu22651%20complete%20spontaneous%20bowel%20movement%5C%2Fweek%20above%20baseline%20for%20%5Cu22652%5C%2F4%20weeks%20were%20considered%20responders.%20Secondary%20outcome%20measures%20included%20stool%20consistency%2C%20bowel%20satisfaction%2C%20straining%2C%20gas%2C%20bloating%2C%20taste%2C%20dissolvability%20and%20quality%20of%20life%20%28QoL%29.%5CnRESULTS%3A%20Seventy-two%20subjects%20%28mixed%20fibre%20%3D%2040%3B%20psyllium%20%3D%2032%29%20were%20enrolled%20and%20two%20from%20psyllium%20group%20withdrew.%20The%20mean%20complete%20spontaneous%20bowel%20movement%5C%2Fweek%20increased%20with%20both%20mixed%20fibre%20%28P%20%26lt%3B%200.0001%29%20and%20psyllium%20%28P%20%3D%200.0002%29%20without%20group%20difference.%20There%20were%2030%20%2875%25%29%20responders%20with%20mixed%20fibre%20and%2024%20%2875%25%29%20with%20psyllium%20%28P%20%3D%200.9%29.%20Stool%20consistency%20increased%20%28P%20%3D%200.04%29%2C%20straining%20%28P%20%3D%200.006%29%20and%20bloating%20scores%20decreased%20%28P%20%3D%200.02%29%20without%20group%20differences.%20Significantly%20more%20patients%20reported%20improvement%20in%20flatulence%20%2853%25%20vs.%2025%25%2C%20P%20%3D%200.01%29%20and%20felt%20that%20mixed%20fibre%20dissolved%20better%20%28P%20%3D%200.02%29%20compared%20to%20psyllium.%20QoL%20improved%20%28P%20%3D%200.0125%29%20with%20both%20treatments%20without%20group%20differences.%5CnCONCLUSIONS%3A%20Mixed%20fibre%20and%20psyllium%20were%20equally%20efficacious%20in%20improving%20constipation%20and%20QoL.%20Mixed%20fibre%20was%20more%20effective%20in%20relieving%20flatulence%2C%20bloating%20and%20dissolved%20better.%20Mixed%20fibre%20is%20effective%20and%20well%20tolerated.%22%2C%22date%22%3A%2207%202016%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fapt.13647%22%2C%22ISSN%22%3A%221365-2036%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22U8LU2X8Y%22%5D%2C%22dateModified%22%3A%222020-08-31T08%3A12%3A30Z%22%7D%7D%2C%7B%22key%22%3A%22CX5RCXDP%22%2C%22library%22%3A%7B%22id%22%3A6784680%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22McRorie%20and%20McKeown%22%2C%22parsedDate%22%3A%222017%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BMcRorie%2C%20J.%20W.%2C%20%26amp%3B%20McKeown%2C%20N.%20M.%20%282017%29.%20Understanding%20the%20Physics%20of%20Functional%20Fibers%20in%20the%20Gastrointestinal%20Tract%3A%20An%20Evidence-Based%20Approach%20to%20Resolving%20Enduring%20Misconceptions%20about%20Insoluble%20and%20Soluble%20Fiber.%20%26lt%3Bi%26gt%3BJournal%20of%20the%20Academy%20of%20Nutrition%20and%20Dietetics%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B117%26lt%3B%5C%2Fi%26gt%3B%282%29%2C%20251%26%23x2013%3B264.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jand.2016.09.021%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jand.2016.09.021%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Understanding%20the%20Physics%20of%20Functional%20Fibers%20in%20the%20Gastrointestinal%20Tract%3A%20An%20Evidence-Based%20Approach%20to%20Resolving%20Enduring%20Misconceptions%20about%20Insoluble%20and%20Soluble%20Fiber%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Johnson%20W.%22%2C%22lastName%22%3A%22McRorie%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicola%20M.%22%2C%22lastName%22%3A%22McKeown%22%7D%5D%2C%22abstractNote%22%3A%22Enduring%20misconceptions%20about%20the%20physical%20effects%20of%20fiber%20in%20the%20gut%20have%20led%20to%20misunderstandings%20about%20the%20health%20benefits%20attributable%20to%20insoluble%20and%20soluble%20fiber.%20This%20review%20will%20focus%20on%20isolated%20functional%20fibers%20%28eg%2C%20fiber%20supplements%29%20whose%20effects%20on%20clinical%20outcomes%20have%20been%20readily%20assessed%20in%20well-controlled%20clinical%20studies.%20This%20review%20will%20also%20focus%20on%20three%20health%20benefits%20%28cholesterol%20lowering%2C%20improved%20glycemic%20control%2C%20and%20normalizing%20stool%20form%20%5Bconstipation%20and%20diarrhea%5D%29%20for%20which%20reproducible%20evidence%20of%20clinical%20efficacy%20has%20been%20published.%20In%20the%20small%20bowel%2C%20clinically%20meaningful%20health%20benefits%20%28eg%2C%20cholesterol%20lowering%20and%20improved%20glycemic%20control%29%20are%20highly%20correlated%20with%20the%20viscosity%20of%20soluble%20fibers%3A%20high%20viscosity%20fibers%20%28eg%2C%20gel-forming%20fibers%20such%20as%20b-glucan%2C%20psyllium%2C%20and%20raw%20guar%20gum%29%20exhibit%20a%20significant%20effect%20on%20cholesterol%20lowering%20and%20improved%20glycemic%20control%2C%20whereas%20nonviscous%20soluble%20fibers%20%28eg%2C%20inulin%2C%20fructooligosaccharides%2C%20and%20wheat%20dextrin%29%20and%20insoluble%20fibers%20%28eg%2C%20wheat%20bran%29%20do%20not%20provide%20these%20viscosity-dependent%20health%20benefits.%20In%20the%20large%20bowel%2C%20there%20are%20only%20two%20mechanisms%20that%20drive%20a%20laxative%20effect%3A%20large%5C%2Fcoarse%20insoluble%20fiber%20particles%20%28eg%2C%20wheat%20bran%29%20mechanically%20irritate%20the%20gut%20mucosa%20stimulating%20water%20and%20mucous%20secretion%2C%20and%20the%20high%20water-holding%20capacity%20of%20gel-forming%20soluble%20fiber%20%28eg%2C%20psyllium%29%20resists%20dehydration.%20Both%20mechanisms%20require%20that%20the%20fiber%20resist%20fermentation%20and%20remain%20relatively%20intact%20throughout%20the%20large%20bowel%20%28ie%2C%20the%20fiber%20must%20be%20present%20in%20stool%29%2C%20and%20both%20mechanisms%20lead%20to%20increased%20stool%20water%20content%2C%20resulting%20in%20bulky%5C%2Fsoft%5C%2Feasy-to-pass%20stools.%20Soluble%20fermentable%20fibers%20%28eg%2C%20inulin%2C%20fructooligosaccharide%2C%20and%20wheat%20dextrin%29%20do%20not%20provide%20a%20laxative%20effect%2C%20and%20some%20fibers%20can%20be%20constipating%20%28eg%2C%20wheat%20dextrin%20and%20fine%5C%2Fsmooth%20insoluble%20wheat%20bran%20particles%29.%20When%20making%20recommendations%20for%20a%20fiber%20supplement%2C%20it%20is%20essential%20to%20recognize%20which%20fibers%20possess%20the%20physical%20characteristics%20required%20to%20provide%20a%20beneficial%20health%20effect%2C%20and%20which%20fiber%20supplements%20are%20supported%20by%20reproducible%2C%20rigorous%20evidence%20of%20one%20or%20more%20clinically%20meaningful%20health%20benefits.%22%2C%22date%22%3A%2202%202017%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.jand.2016.09.021%22%2C%22ISSN%22%3A%222212-2672%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22U8LU2X8Y%22%5D%2C%22dateModified%22%3A%222020-08-31T08%3A12%3A25Z%22%7D%7D%2C%7B%22key%22%3A%22K6TQP3WA%22%2C%22library%22%3A%7B%22id%22%3A6784680%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Curr%5Cu00f2%20et%20al.%22%2C%22parsedDate%22%3A%222017%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BCurr%26%23xF2%3B%2C%20D.%2C%20Ianiro%2C%20G.%2C%20Pecere%2C%20S.%2C%20Bibb%26%23xF2%3B%2C%20S.%2C%20%26amp%3B%20Cammarota%2C%20G.%20%282017%29.%20Probiotics%2C%20fibre%20and%20herbal%20medicinal%20products%20for%20functional%20and%20inflammatory%20bowel%20disorders.%20%26lt%3Bi%26gt%3BBritish%20Journal%20of%20Pharmacology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B174%26lt%3B%5C%2Fi%26gt%3B%2811%29%2C%201426%26%23x2013%3B1449.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fbph.13632%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fbph.13632%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Probiotics%2C%20fibre%20and%20herbal%20medicinal%20products%20for%20functional%20and%20inflammatory%20bowel%20disorders%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Diego%22%2C%22lastName%22%3A%22Curr%5Cu00f2%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gianluca%22%2C%22lastName%22%3A%22Ianiro%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Silvia%22%2C%22lastName%22%3A%22Pecere%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stefano%22%2C%22lastName%22%3A%22Bibb%5Cu00f2%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Giovanni%22%2C%22lastName%22%3A%22Cammarota%22%7D%5D%2C%22abstractNote%22%3A%22Functional%20bowel%20disorders%20%28FBD%29%2C%20mainly%20irritable%20bowel%20syndrome%20%28IBS%29%20and%20functional%20constipation%20%28FC%2C%20also%20called%20chronic%20idiopathic%20constipation%29%2C%20are%20very%20common%20worldwide.%20Inflammatory%20bowel%20disease%20%28IBD%29%2C%20including%20ulcerative%20colitis%20and%20Crohn%26%23039%3Bs%20disease%2C%20although%20less%20common%2C%20has%20a%20strong%20impact%20on%20patients%26%23039%3B%20quality%20of%20life%2C%20as%20well%20as%20being%20highly%20expensive%20for%20our%20healthcare.%20A%20definite%20cure%20for%20those%20disorders%20is%20still%20yet%20to%20come.%20Over%20the%20years%2C%20several%20therapeutic%20approaches%20complementary%20or%20alternative%20to%20traditional%20pharmacological%20treatments%2C%20including%20probiotics%2C%20prebiotics%2C%20synbiotics%2C%20fibre%20and%20herbal%20medicinal%20products%2C%20have%20been%20investigated%20for%20the%20management%20of%20both%20groups%20of%20diseases.%20However%2C%20most%20available%20studies%20are%20biased%20by%20several%20drawbacks%2C%20including%20small%20samples%20and%20poor%20methodological%20quality.%20Probiotics%2C%20in%20particular%20Saccharomyces%20boulardii%20and%20Lactobacilli%20%28among%20which%20Lactobacillus%20rhamnosus%29%2C%20synbiotics%2C%20psyllium%2C%20and%20some%20herbal%20medicinal%20products%2C%20primarily%20peppermint%20oil%2C%20seem%20to%20be%20effective%20in%20ameliorating%20IBS%20symptoms.%20Synbiotics%20and%20fibre%20seem%20to%20be%20beneficial%20in%20FC%20patients.%20The%20probiotic%20combination%20VSL%233%20may%20be%20effective%20in%20inducing%20remission%20in%20patients%20with%20mild-to-moderate%20ulcerative%20colitis%2C%20in%20whom%20Escherichia%20coli%20Nissle%201917%20seems%20to%20be%20as%20effective%20as%20mesalamine%20in%20maintaining%20remission.%20No%20definite%20conclusions%20can%20be%20drawn%20as%20to%20the%20efficacy%20of%20fibre%20and%20herbal%20medicinal%20products%20in%20IBD%20patients%20due%20to%20the%20low%20number%20of%20studies%20and%20the%20lack%20of%20randomized%20controlled%20trials%20that%20replicate%20the%20results%20obtained%20in%20the%20individual%20studies%20conducted%20so%20far.%20Thus%2C%20further%2C%20well-designed%20studies%20are%20needed%20to%20address%20the%20real%20role%20of%20these%20therapeutic%20options%20in%20the%20management%20of%20both%20FBD%20and%20IBD.%5CnLINKED%20ARTICLES%3A%20This%20article%20is%20part%20of%20a%20themed%20section%20on%20Principles%20of%20Pharmacological%20Research%20of%20Nutraceuticals.%20To%20view%20the%20other%20articles%20in%20this%20section%20visit%20http%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2F10.1111%5C%2Fbph.v174.11%5C%2Fissuetoc.%22%2C%22date%22%3A%2206%202017%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fbph.13632%22%2C%22ISSN%22%3A%221476-5381%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22U8LU2X8Y%22%5D%2C%22dateModified%22%3A%222020-08-31T08%3A09%3A14Z%22%7D%7D%5D%7D
Abutair, A. S., Naser, I. A., & Hamed, A. T. (2016). Soluble fibers from psyllium improve glycemic response and body weight among diabetes type 2 patients (randomized control trial). Nutrition Journal, 15(1), 86. https://doi.org/10.1186/s12937-016-0207-4
Garg, P. (2017). Psyllium Husk Should Be Taken at Higher Dose with Sufficient Water to Maximize Its Efficacy. Journal of the Academy of Nutrition and Dietetics, 117(5), 681. https://doi.org/10.1016/j.jand.2017.03.001
Erdogan, A., Rao, S. S. C., Thiruvaiyaru, D., Lee, Y. Y., Coss Adame, E., Valestin, J., & O’Banion, M. (2016). Randomised clinical trial: mixed soluble/insoluble fibre vs. psyllium for chronic constipation. Alimentary Pharmacology & Therapeutics, 44(1), 35–44. https://doi.org/10.1111/apt.13647
McRorie, J. W., & McKeown, N. M. (2017). Understanding the Physics of Functional Fibers in the Gastrointestinal Tract: An Evidence-Based Approach to Resolving Enduring Misconceptions about Insoluble and Soluble Fiber. Journal of the Academy of Nutrition and Dietetics, 117(2), 251–264. https://doi.org/10.1016/j.jand.2016.09.021
Currò, D., Ianiro, G., Pecere, S., Bibbò, S., & Cammarota, G. (2017). Probiotics, fibre and herbal medicinal products for functional and inflammatory bowel disorders. British Journal of Pharmacology, 174(11), 1426–1449. https://doi.org/10.1111/bph.13632